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PSD Antibody / PH and SEC7 domain-containing protein 1

PSD, also called EFA6A, is 63% identical to EFA6B (PSD4) and contains a Sec7 domain adjacent to a PH domain, followed by a C-terminal coiled-coil motif. This gene is mapped to chromosome 10q24. And it encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL (recombinant human protein) (BSA-free format available)

UniProt

A5PKW4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A human partial recombinant protein corresponding to amino acids T536-K803 was used as the immunogen for the PSD antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the PSD antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This PSD antibody is available for research use only.

Storage Conditions

After reconstitution, the PSD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the PSD antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) rat brain and 2) mouse brain with PSD antibody at 0.5ug/ml. Predicted molecular weight ~109 kDa.

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