CCR4 Antibody
CCR4, C-C chemokine receptor type 4, is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194 (cluster of differentiation 194) . The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines. The CCR4 gene is mapped to chromosome 3. Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P51679
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids LVELEVLQDCTFERYLDYAIQATETLAFVH from the human protein were used as the immunogen for the CCR4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This CCR4 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CCR4 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat thymus, 2) mouse thymus and 3) mouse NIH 3T3 lysate with CCR4 antibody at 0.5ug/ml. Predicted molecular weight ~41 kDa.
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