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Galectin 10 Antibody

Eosinophil lysophospholipase, also called Galectin 10 or Gal-10, is an enzyme that in humans is encoded by the CLC gene. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q05315

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant human protein corresponding to amino acids S2-R142 was used as the immunogen for the Galectin 10 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the Galectin 10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Galectin 10 antibody is available for research use only.

Storage Conditions

After reconstitution, the Galectin 10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Galectin 10 antibody should be determined by the researcher.

Location

Nucleus

Image Legend

Western blot testing of human 1) HL-60 and 2) PANC-1 lysate with Galectin 10 antibody at 0.5ug/ml. Predicted molecular weight ~16 kDa.

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