TACI Antibody / Transmembrane activator and CAML interactor
Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) is a protein that in humans is encoded by the TNFRSF13B gene. The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML) . The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 2-5 µg/mL
UniProt
O14836
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant human protein corresponding to amino acids M1-S165 was used as the immunogen for the TACI antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This TACI antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TACI antibody should be determined by the researcher.
Location
Membrane
Image Legend
IHC staining of FFPE human spleen tissue with TACI antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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