IL-17E Antibody / IL-25

Interleukin-25 (IL-25), also known as interleukin-17E (IL-17E), is a protein that in humans is encoded by the IL25 gene. The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.

Product Specifications

CAS Number

9007-83-4

Specifications

Western Blot: 0.5-1 µg/mL, ELISA (Capture) : 0.1-0.5 µg/mL

UniProt

Q9H293

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant human partial protein corresponding to amino acids Y33-G177 was used as the immunogen for the IL-17E antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the IL-17E antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This IL-17E antibody is available for research use only.

Storage Conditions

After reconstitution, the IL-17E antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the IL-17E antibody should be determined by the researcher.

Image Legend

Western blot testing of 1ng of recombinant human protein with IL-17E antibody at 0.5ug/ml. Predicted molecular weight: ~18 kDa (unmodified), 21-26 kDa (glycosylated) .