LIF Antibody / Leukemia inhibitory factor
LIF is a pleiotropic cytokine produced at the maternal-fetal interface which has been shown to play an essential role in implantation in mice. This gene is mapped to 22q11-q12.2, between the Philadelphia translocation BCR gene and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF is produced in high amounts by the human endometrium and the trophoblast itself, and LIF receptors are present on cytotrophoblast cells. LIF could, thus, play a role in modulating HLA-G production and immune tolerance at the maternal-fetal interface.
Product Specifications
Specifications
Western Blot: 0.5-1 µg/mL, ELISA (Capture) : 0.1-0.5 µg/mL
UniProt
P09056
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant mouse partial protein corresponding to amino acids S24-F203 was used as the immunogen for the LIF antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This LIF antibody is available for research use only.
Storage Conditions
Product Datasheet
https://www.nsjbio.com/tds-pdf/lif-antibody-leukemia-inhibitory-factor-rq4084
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the LIF antibody should be determined by the researcher.
CAS Number
9007-83-4
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