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ITF Polyclonal Rabbit pAb

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]

Synonyms

Trefoil factor 3 (Intestinal trefoil factor;hITF;Polypeptide P1.B;hP1.B)

Gene ID

7033

UniProt

Q07654

Cellular Locus

Secreted, extracellular space, extracellular matrix. Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human ITF Polyclonal AA range: 1-50

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC, ELISA

Validated Applications

IHC,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

IHC-p 1:50-200, ELISA (peptide) 1:5000-20000

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES15413-1.pdf

Subcellular Location

Secreted, extracellular space, extracellular matrix . Cytoplasm .

Other Product Names

Trefoil factor 3 (Intestinal trefoil factor; hITF; Polypeptide P1.B; hP1.B)

Gene ID (Human)

7033

SwissProt (Human)

Q07654

Available Sizes

Curated Selection

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