AGRP Antibody
Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
Product Specifications
CAS Number
9007-83-4
Specifications
IHC (FFPE) : 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P56473
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant mouse partial protein corresponding to amino acids S82-T131 was used as the immunogen for the AGRP antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Limitations
This AGRP antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the AGRP antibody should be determined by the researcher.
Location
Cytoplasmic, secreted
Image Legend
Documents
Frequently Asked Questions
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