Batefenterol (Succinate)

[1]Hegde SS, et al. Pharmacologic characterization of GSK-961081 (TD-5959), a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties. J Pharmacol Exp Ther. 2014 Oct;351 (1) :190-9.|[2]Hughes AD, et al. Discovery of (R) -1- (3- ((2-chloro-4- (((2-hydroxy-2- (8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl) ethyl) amino) methyl) -5-methoxyphenyl) amino) -3-oxopropyl) piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate (TD-5959, GSK961081, batefenterol) : first-in-class dual pharmacology multivalent muscarinic antagonist and β? agonist (MABA) for the treatment of chronic obstructive pulmonary disease (COPD) . J Med Chem. 2015 Mar 26;58 (6) :2609-22.|[3]Randomized dose-finding study of batefenterol via dry powder inhaler in patients with COPD