RBP4 Antibody / Retinol Binding Protein 4

RBP4 is also known as RDCCAS. This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.

Product Specifications

CAS Number

9007-83-4

Specifications

Western Blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL, ELISA (Capture; recombinant mouse protein) : 0.1-0.5 µg/mL (BSA-free format available)

UniProt

Q00724

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A recombinant mouse protein corresponding to amino acids E19-L201 was used as the immunogen for the RBP4 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, ELISA (capture)

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide

Reconstitution

After reconstitution, the RBP4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This RBP4 antibody is available for research use only.

Storage Conditions

After reconstitution, the RBP4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the RBP4 antibody should be determined by the researcher.

Location

Cytoplasmic

Image Legend

Western blot testing of 1) mouse liver, 2) rat liver, 3) human placenta and 4) human HepG2 lysate with RBP4 antibody at 0.5ug/ml. Predicted molecular weight ~23 kDa.