Follistatin Antibody / FST
Follistatin also known as activin-binding protein is a protein that in humans is encoded by the FST gene. Follistatin is an autocrine glycoprotein that is expressed in nearly all tissues of higher animals. It is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
Product Specifications
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, ELISA (Capture; human recombinant protein) : 0.1-0.5 µg/mL (BSA-free format available)
UniProt
P19883
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant human protein corresponding to amino acids N31-K261 was used as the immunogen for the Follistatin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA (capture)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
Limitations
This Follistatin antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Follistatin antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) mouse kidney and 2) human MCF7 cell lysate with Follistatin antibody at 0.5ug/ml. Predicted molecular weight ~38 kDa.
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Frequently Asked Questions
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