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Ccl20 Antibody / Mip-3 alpha

Macrophage Inflammatory Protein 3 alpha (MIP-3 alpha), is also called Chemokine, cc motif, ligand 20 (CCL20) . The MIP-3 alpha / CCL20 gene was cloned and sequenced, revealing a four exon, three intron structure, and was localized by FISH analysis to 2q35-q36. MIP3 alpha is predominantly expressed in lymph nodes, appendix, PBL, fetal liver, fetal lung and several cell lines. MIP3 alpha / CCL20 and its receptor CCR6 are markedly up-regulated in psoriasis, and they may play a role in the recruitment of T cells to lesional psoriatic skin.

Product Specifications

CAS Number

9007-83-4

Specifications

Western Blot: 0.5-1 µg/mL, ELISA (Capture; recombinant mouse protein) : 0.1-0.5 µg/mL (BSA-free format available)

UniProt

O89093

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

A recombinant mouse protein corresponding to amino acids A28-M97 was used as the immunogen for the Ccl20 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, ELISA (capture)

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide

Reconstitution

After reconstitution, the Ccl20 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Ccl20 antibody is available for research use only.

Storage Conditions

After reconstitution, the Ccl20 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Ccl20 antibody should be determined by the researcher.

Location

Cytoplasmic, secreted

Image Legend

Western blot testing of 1) rat testis and 2) mouse testis tissue lysate with Ccl20 antibody at 0.5ug/ml. Predicted molecular weight ~11 kDa.

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