Ccl20 Antibody / Mip-3 alpha
Macrophage Inflammatory Protein 3 alpha (MIP-3 alpha), is also called Chemokine, cc motif, ligand 20 (CCL20) . The MIP-3 alpha / CCL20 gene was cloned and sequenced, revealing a four exon, three intron structure, and was localized by FISH analysis to 2q35-q36. MIP3 alpha is predominantly expressed in lymph nodes, appendix, PBL, fetal liver, fetal lung and several cell lines. MIP3 alpha / CCL20 and its receptor CCR6 are markedly up-regulated in psoriasis, and they may play a role in the recruitment of T cells to lesional psoriatic skin.
Product Specifications
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, ELISA (Capture; recombinant mouse protein) : 0.1-0.5 µg/mL (BSA-free format available)
UniProt
O89093
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
A recombinant mouse protein corresponding to amino acids A28-M97 was used as the immunogen for the Ccl20 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA (capture)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
Limitations
This Ccl20 antibody is available for research use only.
Storage Conditions
Product Datasheet
https://www.nsjbio.com/tds-pdf/ccl20-antibody-mip-3-alpha-r32858
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Ccl20 antibody should be determined by the researcher.
Location
Cytoplasmic, secreted
Image Legend
Western blot testing of 1) rat testis and 2) mouse testis tissue lysate with Ccl20 antibody at 0.5ug/ml. Predicted molecular weight ~11 kDa.
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