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Il23r Antibody / Il-23 receptor

Interleukin 23 receptor is a type I cytokine receptor. IL23R is its human gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

Product Specifications

CAS Number

9007-83-4

Specifications

Western Blot: 0.5-1 µg/mL, ELISA (Capture: recombinant mouse protein) : 0.1-0.5 µg/mL (BSA-free format available)

UniProt

Q8K4B4

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

A recombinant mouse protein corresponding to amino acids I25-D233 was used as the immunogen for the Il23r antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, ELISA (capture)

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide

Reconstitution

After reconstitution, the Il23r antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Il23r antibody is available for research use only.

Storage Conditions

After reconstitution, the Il23r antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Il23r antibody should be determined by the researcher.

Prediction Reactivity

Human

Image Legend

Western blot testing of mouse 1) brain, 2) liver and 3) kidney lysate with Il23r antibody at 0.5ug/ml. Expected molecular weight ~72 kDa, observed here at ~58 kDa.

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