Galectin 1 Antibody

Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.

Product Specifications

CAS Number

9007-83-4

Specifications

Western Blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL, ELISA (Capture; rat recombinant protein) : 0.1-0.5 µg/mL (BSA-free format available)

UniProt

P11762

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A recombinant rat protein corresponding to amino acids A2-E135 was used as the immunogen for the Galectin 1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, ELISA (capture)

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide

Reconstitution

After reconstitution, the Galectin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Galectin 1 antibody is available for research use only.

Storage Conditions

After reconstitution, the Galectin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Galectin 1 antibody should be determined by the researcher.

Location

Cytoplasmic, secreted

Image Legend

Western blot testing of 1) rat stomach, 2) rat ovary, 3) rat testis, 4) mouse kidney and 5) human HeLa lysate with Galectin 1 antibody at 0.5ug/ml. Predicted molecular weight ~15 kDa.