TRAIL Antibody
TNF-related apoptosis-inducing ligand (TRAIL), is a protein functioning as a ligand that induces the process of cell death called apoptosis. TRAIL has also been designated CD253 (cluster of differentiation 253). It is a member of Tumor Necrosis Factor Ligand Superfamily. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL has got 281 amino acid proteins. TRAIL mRNA is expressed at significant levels in most normal tissues. TRAIL binds to the death receptors DR4 (TRAIL-RI) and DR5 (TRAIL-RII) and the receptors DcR1 and DcR2, leading to activation of specific kinases and transcription of genes.
Product Specifications
UniProt
P50591
Host
Rabbit
Immunogen
A recombinant protein corresponding to amino acids N40-A272 was used as the immunogen for the TRAIL antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Format
Antigen affinity purified
Buffer
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Reconstitution
Limitations
This TRAIL antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6688054/datasheet/r32840.pdf
CAS Number
9007-83-4
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