Aquaporin 3 Antibody

Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as AQP0/Aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, Aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

Q8R2N1

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Amino acids 122-137 (LYYDAIWAFANNELFV) from the mouse protein were used as the immunogen for the Aquaporin 3 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide

Reconstitution

After reconstitution, the Aquaporin 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This Aquaporin 3 antibody is available for research use only.

Storage Conditions

After reconstitution, the Aquaporin 3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Aquaporin 3 antibody should be determined by the researcher.

Prediction Reactivity

Human

Image Legend

Western blot testing of 1) mouse kidney, 2) mouse brain, 3) rat kidney and 4) rat brain with Aquaporin 3 antibody at 0.5ug/ml. Predicted molecular weight ~32 kDa.