TSH Receptor Antibody
TSHR (Thyroid-Stimulating Hormone Receptor), also called LGR3, is mapped to 14q31.1. The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P16473
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Amino acids 515-538 (ITLERWYAITFAMRLDRKIRLRHA) from the beta subunit of the human protein were used as the immunogen for the TSH Receptor antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
Limitations
This TSH Receptor antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TSH Receptor antibody should be determined by the researcher.
Prediction Reactivity
Human
Image Legend
Frequently Asked Questions
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