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(S) -OPC-51803

(S) -OPC-51803 is an agonist of the vasopressin V2 receptor, with activity in suppressing nocturia and urinary incontinence. (S) -OPC-51803 was evaluated in terms of biological activity and showed a stronger V2 receptor agonist effect compared to its (R) -isomer. The use of (S) -OPC-51803 may improve the patient's ability to control nocturnal polyuria[1].

Product Specifications

CAS Number

192514-57-1

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/s-opc-51803.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(C=C(N2CCCC2)C=C1)Cl)N3C4=CC=CC=C4[C@@H](CCC3)CC(NC(C)C)=O

Molecular Formula

C26H32ClN3O2

Molecular Weight

454.00

References & Citations

[1]Characterization of orally active nonpeptide vasopressin V (2) receptor agonist. Synthesis and biological evaluation of both the (5R) - and (5S) -enantioisomers of 2-[1- (2-Chloro-4-pyrrolidin-1-yl-benzoyl) -2,3,4,5-tetrahydro-1H-1-benzazepin- 5-yl]-N-isopropylacetamide

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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