E2F3 Antibody
Transcription factor E2F3, also known as KIAA0075, is a protein that in humans is encoded by the E2F3 gene. The protein encoded by this gene is a member of the E2F family of transcription factors. By fluorescence in situ hybridization, E2F3 gene is mapped to 6q22.3. The induction of specific E2F activities is an essential component in the MYC pathways that control cell proliferation and cell fate decisions. This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle.
Product Specifications
UniProt
O00716
Host
Rabbit
Immunogen
Amino acids 278-320 (QSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKA-human) were used as the immunogen for the E2F3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Format
Antigen affinity purified
Buffer
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Reconstitution
Limitations
This antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6687859/datasheet/r32617.pdf
CAS Number
9007-83-4
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