EBP1 Antibody / ErbB3-binding protein 1 / PA2G4

Proliferation-associated protein 2G4 (PA2G4), also known as ErbB3-binding protein 1 (EBP1), is a protein that in humans is encoded by the PA2G4 gene. This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional corepressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL

Gene ID

5036

UniProt

Q9UQ80

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids 138-178 (RKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFN-human) were used as the immunogen for the EBP1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the EBP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This EBP1 antibody is available for research use only.

Storage Conditions

After reconstitution, the EBP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the EBP1 antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) rat liver, 2) mouse NIH3T3 and 3) human HepG2 lysate with EBP1 antibody at 0.5ug/ml. Observed molecular weight 42 kDa (p42 isoform) and 48 kDa (p48 isoform) .