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GAB1 Antibody

GRB2-associated-binding protein 1 is a protein that in humans is encoded by the GAB1 gene. It is mapped to 4q31.21. The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

Gene ID

2549

UniProt

Q13480

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Amino acids 72-109 (LTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVR-human) were used as the immunogen for the GAB1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the GAB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This GAB1 antibody is available for research use only.

Storage Conditions

After reconstitution, the GAB1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the GAB1 antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) rat testis and 2) human K562 lysate with GAB1 antibody at 0.5ug/ml. Predicted molecular weight ~76 kDa, also observed at 100-110 kDa.

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