Beta III Tubulin Antibody
Tubulin beta-3 chain is a protein that in humans is encoded by the TUBB3 gene. This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Flow cytometry: 1-3ug/million cells
Gene ID
10381
UniProt
Q13509
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 383-412 (EQFTAMFRRKAFLHWYTGEGMDEMEFTEAE-human) were used as the immunogen for the Beta III Tubulin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This Beta III Tubulin antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Beta III Tubulin antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC testing of FFPE human breast cancer with Beta III Tubulin antibody at 1ug/ml. HIER: steam section in pH6 citrate buffer for 20 min.
Frequently Asked Questions
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