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HVEM Antibody / TNFRSF14

Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, ELISA: 0.5-1 µg/mL (human protein tested) ; request BSA-free format for coating

UniProt

Q92956

Host

Rabbit

Reactivity

Human

Immunogen

Amino acids L39-V202 from the human protein were used as the immunogen for the HVEM antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, ELISA (protein)

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Reconstitution

After reconstitution, the HVEM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This HVEM antibody is available for research use only.

Storage Conditions

After reconstitution, the HVEM antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Differences in protocols and secondary/substrate sensitivity may require the HVEM antibody to be titrated for optimal performance.

Image Legend

Western blot testing of human 1) HeLa and 2) SW620 cell lysate with HVEM antibody at 0.5ug/ml. Expected molecular weight: 30-38 kDa depending on glycosylation level.

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