AAT Antibody / Alpha 1 Antitrypsin / SERPINA1

SERPINA1 is also known as PI, A1A or AAT. This gene is mapped to 14q32.1. The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

P01009

Host

Rabbit

Reactivity

Human, Monkey, Mouse

Immunogen

Amino acids E25-T204 from the human protein were used as the immunogen for the AAT antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the AAT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This AAT antibody is available for research use only.

Storage Conditions

After reconstitution, the AAT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Differences in protocols and secondary/substrate sensitivity may require the AAT antibody to be titrated for optimal performance.

Image Legend

Western blot analysis of 1) human T-47D, 2) monkey COS7 and 3) mouse kidney lysate with AAT antibody at 0.5ug/ml. Alpha 1 Antitrypsin is a glycoprotein with an expected molecular weight of 47-52 kDa.