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PSAT1 Antibody / Phosphoserine aminotransferase

Phosphoserine aminotransferase (PSA), also known as phosphohydroxythreonine aminotransferase (PSAT), is an enzyme that in humans is encoded by the PSAT1 gene. This gene encodes a member of the class-V pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is a phosphoserine aminotransferase and decreased expression may be associated with schizophrenia. Mutations in this gene are also associated with phosphoserine aminotransferase deficiency. Alternative splicing results in multiple transcript variants.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL

UniProt

Q9Y617

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids Q276-L370 from the human protein were used as the immunogen for the PSAT1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the PSAT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This PSAT1 antibody is available for research use only.

Storage Conditions

After reconstitution, the PSAT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Differences in protocols and secondary/substrate sensitivity may require the PSAT1 antibody to be titrated for optimal performance.

Location

Cytoplasmic

Image Legend

Western blot testing of 1) rat pancreas and 2) human HeLa lysate with PSAT1 antibody at 0.5ug/ml. Predicted/observed molecular weight ~40 kDa.

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