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FSH Receptor Antibody / FSHR

The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled receptor (GPCR) . This FSHR gene is mapped to chromosome 2p21 by fluorescence in situ hybridization. The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

P23945

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids C18-N187 from the human protein were used as the immunogen for the FSH Receptor antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the FSH Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This FSH Receptor antibody is available for research use only.

Storage Conditions

After reconstitution, the FSH Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Differences in protocols and secondary/substrate sensitivity may require the FSH Receptor antibody to be titrated for optimal performance.

Image Legend

Western blot testing of 1) rat testis, 2) rat ovary, 3) mouse testis, 4) mouse ovary and 5) human HeLa lysate with FSH Receptor antibody at 0.5ug/ml. Predicted/observed molecular weight: ~78 kDa.

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