ADK Antibody / Adenosine kinase

Adenosine kinase is an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL

UniProt

P55263

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids K165-T351 from the human protein were used as the immunogen for the ADK antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, IF

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the ADK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This ADK antibody is available for research use only.

Storage Conditions

After reconstitution, the ADK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Differences in protocols and secondary/substrate sensitivity may require the ADK antibody to be titrated for optimal performance.

Location

Cytoplasmic, nuclear

Image Legend

Western blot testing of 1) rat liver, 2) rat kidney, 3) rat stomach, 4) rat PC-12, 5) mouse kidney, 6) mouse stomach and 7) mouse NIH 3T3 cell lysate with ADK antibody. Expected molecular weight: 40-45 kDa.