Pf4 Antibody / Platelet factor 4
Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . By in situ hybridization, the CXCL4 gene is mapped to chromosome 4q12-q21. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL, ELISA: 0.1-0.5 µg/mL (mouse protein tested) ; request BSA-free format for coating
UniProt
Q9Z126
Host
Rabbit
Reactivity
Mouse
Immunogen
Amino acids V30-S105 from the mouse protein were used as the immunogen for the Pf4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, ELISA (protein)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This Pf4 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Pf4 antibody should be determined by the researcher.
Location
Cytoplasmic, membranous
Image Legend
IHC staining of FFPE mouse lung tissue with Pf4 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Documents
Frequently Asked Questions
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