CGRP Antibody / CALCA / Calcitonin

Calcitonin gene-related peptide 1, also known as CALCA, is a peptide hormone synthesized by the parafollicular cells of the thyroid. It is mapped to 11p15.2. Calcitonin belongs to the calcitonin-like protein family. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

IHC (FFPE) : 2-5 µg/mL

Gene ID

12310

UniProt

Q99JA0

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Amino acids SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF were used as the immunogen for the CGRP antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the CGRP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This CGRP antibody is available for research use only.

Storage Conditions

After reconstitution, the CGRP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the CGRP antibody should be determined by the researcher.

Location

Cytoplasmic

Image Legend

IHC staining of FFPE rat brain tissue with CGRP antibody, HRP-secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.