GLAST Antibody / EAAT1 / SLC1A3
Solute carrier family 1 (glial high-affinity glutamate transporter), member 3, also known as SLC1A3, EAAT1 or GLAST, is a protein that in humans is encoded by the SLC1A3 gene. This gene is a member of high affinity glutamate transporter family. It is mapped to chromosome 5p13.2 by fluorescence in situ hybridization (FISH) . And this gene transports L-glutamate and also L- and D-aspartate. It is essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Furthermore, this gene acts as a symport by cotransporting sodium.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
Gene ID
6507
UniProt
P43003
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Amino acids RMERFQQGVRKRTLLAKKKVQNITKEDVK were used as the immunogen for the GLAST antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This GLAST antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the GLAST antibody should be determined by the researcher.
Location
Cytoplasmic, membranous
Image Legend
Western blot testing of 1) rat brain and 2) mouse brain lysate with GLAST antibody. Predicted molecular weight: 55-60 kDa.
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