SIP Antibody / CACYBP
SIAH Interacting Protein/SIP is a protein that in humans is encoded by the CACYBP gene. The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. In addition, it probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL, Immunocytochemistry (FFPE) : 1-2 µg/mL
Gene ID
27101
UniProt
Q9HB71
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids QKDLEEVKVLLEKATRKRVRDALTAEKSKIETEIKNKMQQK from the human protein were used as the immunogen for the SIP antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, ICC
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This SIP antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Location
Nuclear, cytoplasmic
Image Legend
Western blot testing of 1) rat brain, 2) mouse testis and 3) human SW620 lysate with SIP antibody. Expected/observed molecular weight ~26 kDa.
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