CCT3 Antibody / TCP1 gamma
T-complex protein 1 subunit gamma is a protein that in humans is encoded by the CCT3 gene. The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, FACS: 1-3ug/10^6 cells, IHC (FFPE) : 1-2 µg/mL, IF/ICC (FFPE) : 2-4 µg/mL
Gene ID
7203
UniProt
P49368
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids EPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQ were used as the immunogen for the CCT3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, IHC-P, IF/ICC
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This CCT3 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CCT3 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of 1) rat kidney and 2) human HeLa lysate with CCT3 antibody. Expected molecular weight ~61 kDa.
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