WNK1 Antibody
WNK lysine deficient protein kinase 1, also known as WNK1, is an enzyme that in humans is encoded by the WNK1 gene. The human gene is located on short arm of chromosome 12 (12p13.3) . This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
Gene ID
65125
UniProt
Q9H4A3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids DNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSED from the human protein were used as the immunogen for the WNK1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This WNK1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the WNK1 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of rat testis lysate with WNK1 antibody. Expected molecular weight: 206-300 kDa (6 isoforms) .
Frequently Asked Questions
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