PCNA Antibody
Proliferating cell nuclear antigen (PCNA) was originally identified by immunofluorescence as a nuclear protein whose appearance correlated with the proliferative state of the cell. PCNA/cyclin has been localized by in situ hybridization to the short arm of human chromosome 20 with a peak of grains over band 20p13. PCNA gene is present in single copy and has 6 exons. It spans 4,961 bp. Synthesis of the nuclear protein cyclin and DNA in quiescent mouse fibroblasts is coordinately induced by serum and purified growth factors. PCNA controls establishment of sister chromatid cohesion during S phase.
Product Specifications
CAS Number
9007-83-4
Host
Mouse
Immunogen
PCNA recombinant protein was used as the immunogen for this PCNA antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Applications
WB, IHC-P, IHC-F, ICC
Format
Ascites
Buffer
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Reconstitution
Limitations
This PCNA antibody is available for research use only.
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