FZD1 Antibody / Frizzled 1
Frizzled-1 (Frizzled homolog 1) is a protein that in humans is encoded by the FZD1 gene. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signalingproteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
Product Specifications
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
Q9UP38
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids YIAGFLLEDRVVCNDKFAEDGARTVAQG TKKE of human Frizzled 1 were used as the immunogen for the FZD1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This FZD1 antibody is available for research use only.
Storage Conditions
Product Datasheet
https://www.nsjbio.com/tds-pdf/fzd1-antibody-frizzled-1-r32354
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the FZD1 antibody should be determined by the researcher.
CAS Number
9007-83-4
Location
Cytoplasmic, membrane
Image Legend
Western blot testing of human 1) 22RV1 and 2) 293 cell lysate with FZD1 antibody. Predicted/observed molecular weight ~71 kDa.
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