FZD1 Antibody / Frizzled 1
Frizzled-1 (Frizzled homolog 1) is a protein that in humans is encoded by the FZD1 gene. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signalingproteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
Q9UP38
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids YIAGFLLEDRVVCNDKFAEDGARTVAQG TKKE of human Frizzled 1 were used as the immunogen for the FZD1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This FZD1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the FZD1 antibody should be determined by the researcher.
Location
Cytoplasmic, membrane
Image Legend
Western blot testing of human 1) 22RV1 and 2) 293 cell lysate with FZD1 antibody. Predicted/observed molecular weight ~71 kDa.
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