CYLD Antibody
CYLD is localized on the long arm of chromosome 16. This gene encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
Q9NQC7
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids 618-956 of human CYLD were used as the immunogen for the CYLD antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This CYLD antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CYLD antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of 1) rat testis, 2) rat brain and 3) human HeLa lysate with CYLD antibody. Predicted/observed molecular weight ~107 kDa.
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