NLRC4 Antibody / CARD12
NLR family CARD domain-containing protein 4, also known as CARD12, is a protein that in humans is encoded by the NLRC4 gene. It is mapped to 2p22.3. This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
Q9NPP4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids KILAQNLHNLVKLSILDLSENYLEKDGNEALHELIDR of human NLRC4/CARD12 were used as the immunogen for the NLRC4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This NLRC4 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the NLRC4 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) human 22RV1, 2) RH35 and 3) mouse NIH3T3 lysate with NLRC4 antibody. Expected/observed molecular weight ~116 kDa.
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