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FGF23 Antibody

Fibroblast growth factor 23 is a protein that in humans is encoded by the FGF23 gene. This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR) . Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC) .

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.1-0.5 µg/mL

UniProt

Q9EPC2

Host

Rabbit

Reactivity

Mouse

Immunogen

Amino acids 48-251 of mouse FGF23 were used as the immunogen for the FGF23 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the FGF23 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This FGF23 antibody is available for research use only.

Storage Conditions

After reconstitution, the FGF23 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the FGF23 antibody should be determined by the researcher.

Image Legend

Western blot testing of mouse testis lysate with FGF23 antibody. Predicted molecular weight 28~32 kDa.

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