GJC2 Antibody

Gap junction gamma-2 (GJC2), also known as connexin-46.6 (Cx46.6) and connexin-47 (Cx47) and gap junction alpha-12 (GJA12), is a protein that in humans is encoded by the GJC2 gene. It is mapped to 1q42.13. This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.1-0.5 µg/mL

UniProt

Q5T442

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids VVRAAERARAHDQNLANLALQALRDGAAAGDRD of human GJC2 were used as the immunogen for the GJC2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the GJC2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This GJC2 antibody is available for research use only.

Storage Conditions

After reconstitution, the GJC2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the GJC2 antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) rat brain, 2) mouse brain, 3) human U20S and 4) human HeLa lysate with GJC2 antibody. Expected/observed molecular weight ~47 kDa.