Syntaxin 1a Antibody
Syntaxin 1a is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) -Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc) . Syntaxins bind synaptotagminin a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. Syntaxin 1a is a key protein in ion channel regulation and synaptic exocytosis.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
Q16623
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids MKDRTQELRTAKDSDDDDDVAVTVDRDR of human Syntaxin 1a were used as the immunogen for the Syntaxin 1a antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This Syntaxin 1a antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Syntaxin 1a antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat brain, 2) mouse brain and 3) human U87 lysate with Syntaxin 1a antibody. Expected molecular weight ~35 kDa.
Frequently Asked Questions
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