11β-HSD1-IN-10
Product Specifications
UNSPSC Description
11β-HSD1-IN-10 (compound c3a) is a potent 11β-HSD1 inhibitor (IC50=1.8 µM for human). 11β-HSD1-IN-10 can be used in studies of obesity, hyperglycemia and cognitive impairment[1].
Target Antigen
11β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/11β-hsd1-in-10.html
Solubility
10 mM in DMSO
Smiles
C1=CC=C2C(=C1)N=C(CC(=O)C3=CC(=CC=C3)C(F)(F)F)O2
Molecular Weight
305.25
References & Citations
[1]Naredo-Gonzalez G, et al. Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19F-Magnetic Resonance Spectroscopy. Sci Rep. 2022 Sep 29;12(1):16268.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W324220/11β-HSD1-IN-10-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W324220/
Clinical Information
No Development Reported
CAS Number
849021-37-0
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