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ATXN1 Antibody / Ataxin 1

Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. The ATXN1 gene had been mapped to 6p23 by in situ hybridization. Ataxin-1 (ATXN1), a causative factor for spinocerebellar ataxia type 1 (SCA1), and the related Brother of ATXN1 (BOAT1) are human proteins involved in transcriptional repression. ATXN1 and BOAT1 might participate in several Notch-controlled developmental and pathological processes.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.1-0.5 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells

UniProt

P54253

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids ESRKLEKSEDEPPLTLPKPSLIPQEVKICIE of human Ataxin 1 were used as the immunogen for the ATXN1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, IF, FACS

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the ATXN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This ATXN1 antibody is available for research use only.

Storage Conditions

After reconstitution, the ATXN1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the ATXN1 antibody should be determined by the researcher.

Location

Cytoplasm, Nucleus

Image Legend

Western blot testing of human 1) MCF7, 2) COLO-320 and 3) PANC-1 lysate with ATXN1 antibody. Commonly observed molecular weight: 87-105 kDa.

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