ATXN1 Antibody / Ataxin 1
Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. The ATXN1 gene had been mapped to 6p23 by in situ hybridization. Ataxin-1 (ATXN1), a causative factor for spinocerebellar ataxia type 1 (SCA1), and the related Brother of ATXN1 (BOAT1) are human proteins involved in transcriptional repression. ATXN1 and BOAT1 might participate in several Notch-controlled developmental and pathological processes.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
P54253
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids ESRKLEKSEDEPPLTLPKPSLIPQEVKICIE of human Ataxin 1 were used as the immunogen for the ATXN1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This ATXN1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ATXN1 antibody should be determined by the researcher.
Location
Cytoplasm, Nucleus
Image Legend
Western blot testing of human 1) MCF7, 2) COLO-320 and 3) PANC-1 lysate with ATXN1 antibody. Commonly observed molecular weight: 87-105 kDa.
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