LCN2 Antibody / Lipocalin 2 / NGAL

Europhile gelatinase-associated lipocalin (NGAL) is a protein that in humans is encoded by the LCN2 gene. The binding of lipocalin-2 to bacterial siderophores is important in the innate immune response to bacterial infection. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL, IHC (Frozen) : 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL (rat protein tested) ; request BSA-free format for coating

UniProt

P30152

Host

Rabbit

Reactivity

Mouse, Rat, Human

Immunogen

Amino acids 21-198 of rat Lipocalin 2 were used as the immunogen for the LCN2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, IHC-F, ELISA (protein)

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide

Reconstitution

After reconstitution, the LCN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This LCN2 antibody is available for research use only.

Storage Conditions

After reconstitution, the LCN2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the LCN2 antibody should be determined by the researcher.

Location

Cytoplasmic

Image Legend

Western blot testing of 1) mouse lung and 2) mouse intestine lysate with LCN2 antibody. Predicted/observed molecular weight: 22-25 kDa.

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