OMG Antibody

Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene. This gene is mapped to 17q11-q12. OMG, like neurofibromin (NF1), has growth suppressive effects and downregulates mitogenic signaling pathways closely related to those influenced by neurofibromin. Overexpression of OMG alters mitogenic signaling in fibroblasts. Cells overexpressing OMG grow more slowly in serum compared to controls and show a partial G1 block upon cell cycle analysis.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.1-0.5 µg/mL

UniProt

P23515

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids YNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPR of human OMG were used as the immunogen for the OMG antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the OMG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This OMG antibody is available for research use only.

Storage Conditions

After reconstitution, the OMG antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the OMG antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) rat brain, 2) mouse brain and 3) human U87 lysate with OMG antibody. Predicted molecular weight: ~50/150 kDa (unmodified/glycosylated) .