Lipocalin 2 Antibody (NGAL, LCN2)
Europhile gelatinase-associated lipocalin (NGAL) is a protein that in humans is encoded by the LCN2 gene. The binding of lipocalin-2 to bacterial siderophores is important in the innate immune response to bacterial infection. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P11672
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Amino acids 21-200 of mouse Lipocalin 2 were used as the immunogen for the Lipocalin 2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IHC-F, ELISA (protein)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
Limitations
This Lipocalin 2 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Lipocalin 2 antibody should be determined by the researcher.
Location
Cytoplasmic, secreted
Image Legend
Western blot testing of 1) rat spleen and 2) rat lung lysate with Lipocalin 2 antibody. Predicted/observed molecular weight: 22-25 kDa.
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