SLC2A2 Antibody

SLC2A2, also known as Glucose transporter 2 (GLUT2), is a transmembrane carrier protein that enables protein facilitatedglucose movement across cell membranes. This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM) . Alternative splicing results in multiple transcript variants of this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL

UniProt

P11168

Host

Rabbit

Reactivity

Human

Immunogen

Amino acids ETKGKSFEEIAAEFQKKSGSAHRPKAAVE of human SLC2A2 were used as the immunogen for the SLC2A2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the SLC2A2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This SLC2A2 antibody is available for research use only.

Storage Conditions

After reconstitution, the SLC2A2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the SLC2A2 antibody should be determined by the researcher.

Location

Membrane

Image Legend

Western blot testing of 1) human PANC, 2) A549 and 3) HT1080 lysate with SLC2A2 antibody. Expected molecular weight: 57~70 kDa depending on glycosylation level, observed here at ~50 kDa.