GLP-1 Antibody / Glucagon-like peptide 1

GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells 'glucose-competent' and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue. It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 0.5-1 µg/mL, Immunofluorescence: 1-2 µg/mL

UniProt

P01275

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids HSQGTFTSDYSKYLDSRRAQDFVQWLMNT of human Glucagon-like peptide 1 were used as the immunogen for the GLP-1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

IHC-P, IF

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the GLP-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This GLP-1 antibody is available for research use only.

Storage Conditions

After reconstitution, the GLP-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the GLP-1 antibody should be determined by the researcher.

Location

Cytoplasmic

Image Legend

IHC testing of human pancreatic cancer tissue with GLP-1 antibody. HIER: Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to staining.