BAG3 Antibody / BAG family molecular chaperone regulator 3

BAG family molecular chaperone regulator 3 (BAG3) inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL

UniProt

O95817

Host

Rabbit

Reactivity

Human

Immunogen

Amino acids 100-561 of human BAG3 were used as the immunogen for the BAG3 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Reconstitution

After reconstitution, the BAG3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This BAG3 antibody is available for research use only.

Storage Conditions

After reconstitution, the BAG3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the BAG3 antibody should be determined by the researcher.

Location

Cytoplasmic, some nuclear

Image Legend

IHC testing of FFPE human lung cancer tissue with BAG3 antibody. HIER: Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to staining.