SOX1 Antibody
SOX1 (for Sex determining region Y-box 1), located in 13q34, is a transcription factor in the Sox protein family. It means that this intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. SOX1 expression is restricted to neuroectodermin the tetrapod embryo. It is expressed particularly in the ventral striatum.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
O00570
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids QHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHR of human SOX1 were used as the immunogen for the SOX1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Limitations
This SOX1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SOX1 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat brain and 2 mouse NIH3T3 lysate with SOX1 antibody. Predicted/observed molecular weight ~39 kDa.
Frequently Asked Questions
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